Hand osteoarthritis in relation to mortality and incidence of cardiovascular disease: data from the Framingham Heart Study
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Abstract
OBJECTIVES:
To study whether hand osteoarthritis (OA) is associated with increased mortality and cardiovascular events in a large community based cohort (Framingham Heart Study) in which OA, mortality and cardiovascular events have been carefully assessed.
CONCLUSIONS:
Symptomatic hand OA, but not radiographic hand OA, was associated with an increased risk of coronary heart disease events. The results suggest an effect of pain, which may be a possible marker of inflammation.
Para estudiar si la osteoartritis de la mano (OA) se asocia con un aumento de la mortalidad y los eventos cardiovasculares en una cohorte de base amplia comunidad (Framingham Heart Study) en el que la OA, la mortalidad y los eventos cardiovasculares se han evaluado cuidadosamente.
Mano OA sintomática, pero no mano OA radiográfica, se asoció con un mayor riesgo de eventos de enfermedad coronaria. Los resultados sugieren un efecto de dolor, que puede ser un posible marcador de la inflamación.
KEYWORDS:
Cardiovascular Disease; Epidemiology; Hand Osteoarthritis; Osteoarthritis
- PMID: 24047870 PMCID:PMC3959628 DOI: 10.1136/annrheumdis-2013-203789
- [PubMed – indexed for MEDLINE]